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Synthetic ACTH (4-10) fragment analog

Semax Calculator

Dosage and reconstitution math for Semax. A synthetic heptapeptide derived from a modified ACTH 4-10 fragment, studied for neurotropic signaling without classical adrenocortical activity.

Reconstitution calculator

Pre-filled with common defaults for Semax. Adjust any field to match your own vial.

mg
mL
Draw to
units on the syringe
Equivalent volume: mL
Concentration
mcg / mL
Per syringe unit
mcg / unit
Show the math

Enter values above to see the step-by-step math.

Preview of the illustrated reconstitution guide
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Free Illustrated Reconstitution Guide (PDF)

8-step visual walkthrough with photos and tips — from gathering supplies to drawing your dose. Educational only — not medical advice.

Semax reconstitution diagram Semax: 10 mg vial mixed with 3 mL bacteriostatic water yields 3.33 mg/mL. A 500 mcg dose draws to 15 units on a U-100 syringe. 1 Reconstitute 10 mg vial + 3 mL BAC water 2 Calculate concentration 3.33 mg/mL 10 mg ÷ 3 mL = 3.33 concentration 3 Convert dose to volume 500 mcg dose 500 mcg ÷ 3333.33 mcg/mL = 0.15 mL 4 Draw to mark 0 25 50 75 100 15 units U-100 10 mg vial · 3 mL water · 3.33 mg/mL · 500 mcg dose → 0.15 mL → 15 units on U-100

Semax dosage calculator

The Semax dosage calculator above converts a target dose into exact syringe units based on your vial size and how much bacteriostatic water you used to reconstitute it. Semax is commonly sold in 5 mg, 10 mg, 30 mg vials. The calculator supports both U-100 and U-40 insulin syringes and flags draws that are too large for the syringe barrel or too small to measure accurately. A synthetic heptapeptide derived from a modified ACTH 4-10 fragment, studied for neurotropic signaling without classical adrenocortical activity. Enter your target dose in the calculator above to see the exact number of units to draw.

Semax dosage chart

Sample doseConcentrationVolume to drawUnits on U-100
250 mcg3.33333 mg/mL0.075 mL7.5
500 mcg3.33333 mg/mL0.15 mL15
1000 mcg3.33333 mg/mL0.3 mL30
2000 mcg3.33333 mg/mL0.6 mL60
4000 mcg3.33333 mg/mL1.2 mL120

Semax and ACTH analog peptides

Semax is a Synthetic ACTH (4-10) fragment analog. A synthetic heptapeptide derived from a modified ACTH 4-10 fragment, studied for neurotropic signaling without classical adrenocortical activity.

See all ACTH analog peptides →

How to reconstitute Semax

Reconstituting Semax is the same unit-conversion process used for any lyophilized peptide:

  1. Draw your chosen volume of bacteriostatic water into a syringe.
  2. Inject the bacteriostatic water slowly down the side of the Semax vial — do not shoot it directly onto the powder.
  3. Swirl gently until the powder fully dissolves. Do not shake.
  4. Store the reconstituted vial refrigerated.
  5. To dose, calculate your draw volume: divide your target dose by the concentration (vial mg ÷ water mL = mg/mL). The calculator above does this automatically.

For Semax specifically, 5 mg, 10 mg, 30 mg vials are common. A typical reconstitution adds 2 mL of bacteriostatic water, producing a concentration of 5 mg/mL for the 10 mg vial size.

Semax half-life and storage

Published work reports a short plasma half-life for unmodified Semax, though downstream neurochemical effects measured in research have been reported to extend beyond the circulating half-life.

Lyophilized Semax is typically stored refrigerated. Reconstituted solutions are commonly refrigerated and protected from light.

Common Semax dosing mistakes

  • Confusing mg and mcg. 1 mg = 1,000 mcg. Always convert to the same unit before computing the draw.
  • Using a U-40 syringe with U-100 math. Same printed mark, 2.5× the physical volume. Always check the syringe label.
  • Not labeling the vial. Write the reconstitution date and concentration on the vial the moment you mix it.
  • Under-diluting. If your draw is less than about 1 unit, the volume is too small to read accurately — add more bacteriostatic water next time.

Semax stacks

Semax is one of the ingredients in what is commonly referred to as the Nootropic stack . These are terms used in online peptide communities to describe specific combinations. See the stack pages for the full composition and calculator links.

Semax FAQ

What is Semax? +
Semax is a Synthetic ACTH (4-10) fragment analog. A synthetic heptapeptide derived from a modified ACTH 4-10 fragment, studied for neurotropic signaling without classical adrenocortical activity.
How do I calculate my Semax dose? +
Use the calculator above. Enter your vial size (5 mg, 10 mg, 30 mg are common for Semax), the amount of bacteriostatic water you added, and your target dose. The calculator returns the exact number of syringe units to draw.
What vial sizes does Semax come in? +
Semax is commonly available in 5 mg, 10 mg, 30 mg vials.
How long does Semax last? +
Semax's reported half-life is Short (parent).
How should I store Semax? +
Lyophilized Semax is typically stored refrigerated. Reconstituted solutions are commonly refrigerated and protected from light.