Semax Calculator

Semax dosage calculator

The Semax dosage calculator above converts a target dose into exact syringe units based on your vial size and how much bacteriostatic water you used to reconstitute it. Semax is commonly sold in 5 mg, 10 mg, 30 mg vials. The calculator supports both U-100 and U-40 insulin syringes and flags draws that are too large for the syringe barrel or too small to measure accurately. A synthetic heptapeptide derived from a modified ACTH 4-10 fragment, studied for neurotropic signaling without classical adrenocortical activity. Enter your target dose in the calculator above to see the exact number of units to draw.

Semax dosage chart

Semax and ACTH analog peptides

Semax is a Synthetic ACTH (4-10) fragment analog. A synthetic heptapeptide derived from a modified ACTH 4-10 fragment, studied for neurotropic signaling without classical adrenocortical activity.

Semax is a synthetic heptapeptide analog corresponding to a modified version of the 4-10 fragment of adrenocorticotropic hormone (ACTH), developed in Russia. It lacks the classic adrenocortical-stimulating activity of the parent hormone. Published research — primarily from Russian laboratories — has studied Semax in animal and human research contexts involving cognitive performance, neuroprotection, and recovery after ischemic events. Semax has been registered as a pharmaceutical in Russia but is not approved by the FDA in the United States. Research-grade Semax is labeled for laboratory use only.

See all ACTH analog peptides →

How to reconstitute Semax

Research vendors typically offer Semax in 5 mg, 10 mg, or 30 mg lyophilized vials. Reconstitution with 2–5 mL of bacteriostatic water is commonly reported.

Reconstituting Semax is the same unit-conversion process used for any lyophilized peptide:

1. Draw your chosen volume of bacteriostatic water into a syringe.
2. Inject the bacteriostatic water slowly down the side of the Semax vial — do not shoot it directly onto the powder.
3. Swirl gently until the powder fully dissolves. Do not shake.
4. Store the reconstituted vial refrigerated.
5. To dose, calculate your draw volume: divide your target dose by the concentration (vial mg ÷ water mL = mg/mL). The calculator above does this automatically.

For Semax specifically, 5 mg, 10 mg, 30 mg vials are common. A typical reconstitution adds 2 mL of bacteriostatic water, producing a concentration of 5 mg/mL for the 10 mg vial size.

Semax half-life and storage

Published work reports a short plasma half-life for unmodified Semax, though downstream neurochemical effects measured in research have been reported to extend beyond the circulating half-life.

Lyophilized Semax is typically stored refrigerated. Reconstituted solutions are commonly refrigerated and protected from light.

Common Semax dosing mistakes

Most Semax draw errors are unit errors, not arithmetic errors: confusing mg with mcg (1 mg = 1,000 mcg), or reading a U-40 syringe with U-100 math — the same printed mark holds 2.5× the volume. Two more worth avoiding: leaving the vial unlabeled, so the concentration and reconstitution date are lost, and under-diluting to the point where the draw is under about one unit and can no longer be read accurately.

Each of these is covered in full in the guides: reconstitution math from first principles, U-100 vs U-40 syringes, storage and shelf life, and how to reconstitute peptides.

Semax stacks

Semax is one of the ingredients in what is commonly referred to as the Nootropic stack . These are terms used in online peptide communities to describe specific combinations. See the stack pages for the full composition and calculator links.