Sermorelin Calculator
Dosage and reconstitution math for Sermorelin. A 29-amino-acid truncated GHRH analog that binds pituitary GHRH receptors to stimulate endogenous growth hormone release.
Reconstitution calculator
Pre-filled with common defaults for Sermorelin. Adjust any field to match your own vial.
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Enter values above to see the step-by-step math.
Free Illustrated Reconstitution Guide (PDF)
8-step visual walkthrough with photos and tips — from gathering supplies to drawing your dose. Educational only — not medical advice.
Sermorelin dosage calculator
The Sermorelin dosage calculator above converts a target dose into exact syringe units based on your vial size and how much bacteriostatic water you used to reconstitute it. Sermorelin is commonly sold in 2 mg, 5 mg, 10 mg, 15 mg vials. The calculator supports both U-100 and U-40 insulin syringes and flags draws that are too large for the syringe barrel or too small to measure accurately. A 29-amino-acid truncated GHRH analog that binds pituitary GHRH receptors to stimulate endogenous growth hormone release. Enter your target dose in the calculator above to see the exact number of units to draw.
Sermorelin dosage chart
| Sample dose | Concentration | Volume to draw | Units on U-100 |
|---|---|---|---|
| 190 mcg | 2.5 mg/mL | 0.076 mL | 7.6 |
| 380 mcg | 2.5 mg/mL | 0.152 mL | 15.2 |
| 750 mcg | 2.5 mg/mL | 0.3 mL | 30 |
| 1500 mcg | 2.5 mg/mL | 0.6 mL | 60 |
| 3000 mcg | 2.5 mg/mL | 1.2 mL | 120 |
Sermorelin and GHRH peptides
Sermorelin is a Truncated GHRH (1-29) analog. A 29-amino-acid truncated GHRH analog that binds pituitary GHRH receptors to stimulate endogenous growth hormone release. The same molecule is the active ingredient in Geref, which are FDA-approved prescription medications manufactured by their respective companies. Research-use Sermorelin is regulated differently and is not approved for human consumption. Other peptides in the GHRH class include CJC-1295 (no DAC) , CJC-1295 with DAC , and Tesamorelin .
How to reconstitute Sermorelin
Reconstituting Sermorelin is the same unit-conversion process used for any lyophilized peptide:
- Draw your chosen volume of bacteriostatic water into a syringe.
- Inject the bacteriostatic water slowly down the side of the Sermorelin vial — do not shoot it directly onto the powder.
- Swirl gently until the powder fully dissolves. Do not shake.
- Store the reconstituted vial refrigerated.
- To dose, calculate your draw volume: divide your target dose by the concentration (vial mg ÷ water mL = mg/mL). The calculator above does this automatically.
For Sermorelin specifically, 2 mg, 5 mg, 10 mg, 15 mg vials are common. A typical reconstitution adds 2 mL of bacteriostatic water, producing a concentration of 5 mg/mL for the 10 mg vial size.
Sermorelin half-life and storage
Published pharmacokinetic studies report a short plasma half-life of approximately 10–20 minutes for sermorelin.
Lyophilized sermorelin is typically stored refrigerated at 2–8 °C. Reconstituted solutions are commonly kept refrigerated and protected from light; published stability data for compounded sermorelin typically references a multi-week window under refrigeration.
Common Sermorelin dosing mistakes
- Confusing mg and mcg. 1 mg = 1,000 mcg. Always convert to the same unit before computing the draw.
- Using a U-40 syringe with U-100 math. Same printed mark, 2.5× the physical volume. Always check the syringe label.
- Not labeling the vial. Write the reconstitution date and concentration on the vial the moment you mix it.
- Under-diluting. If your draw is less than about 1 unit, the volume is too small to read accurately — add more bacteriostatic water next time.