Melanotan-2 Calculator
Dosage and reconstitution math for Melanotan-2. A synthetic cyclic heptapeptide analog of alpha-MSH that binds to melanocortin receptors including MC1R, MC3R, MC4R, and MC5R.
Reconstitution calculator
Pre-filled with common defaults for Melanotan-2. Adjust any field to match your own vial.
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Enter values above to see the step-by-step math.
Free Illustrated Reconstitution Guide (PDF)
8-step visual walkthrough with photos and tips — from gathering supplies to drawing your dose. Educational only — not medical advice.
Melanotan-2 dosage calculator
The Melanotan-2 dosage calculator above converts a target dose into exact syringe units based on your vial size and how much bacteriostatic water you used to reconstitute it. Melanotan-2 is commonly sold in 10 mg vials. The calculator supports both U-100 and U-40 insulin syringes and flags draws that are too large for the syringe barrel or too small to measure accurately. A synthetic cyclic heptapeptide analog of alpha-MSH that binds to melanocortin receptors including MC1R, MC3R, MC4R, and MC5R. Enter your target dose in the calculator above to see the exact number of units to draw.
Melanotan-2 dosage chart
| Sample dose | Concentration | Volume to draw | Units on U-100 |
|---|---|---|---|
| 250 mcg | 2 mg/mL | 0.125 mL | 12.5 |
| 500 mcg | 2 mg/mL | 0.25 mL | 25 |
| 1000 mcg | 2 mg/mL | 0.5 mL | 50 |
| 2000 mcg | 2 mg/mL | 1 mL | 100 |
| 4000 mcg | 2 mg/mL | 2 mL | 200 |
Melanotan-2 and Melanocortin peptides
Melanotan-2 is a Synthetic melanocortin agonist. A synthetic cyclic heptapeptide analog of alpha-MSH that binds to melanocortin receptors including MC1R, MC3R, MC4R, and MC5R. Other peptides in the Melanocortin class include PT-141 (Bremelanotide) .
See all Melanocortin peptides →
How to reconstitute Melanotan-2
Reconstituting Melanotan-2 is the same unit-conversion process used for any lyophilized peptide:
- Draw your chosen volume of bacteriostatic water into a syringe.
- Inject the bacteriostatic water slowly down the side of the Melanotan-2 vial — do not shoot it directly onto the powder.
- Swirl gently until the powder fully dissolves. Do not shake.
- Store the reconstituted vial refrigerated.
- To dose, calculate your draw volume: divide your target dose by the concentration (vial mg ÷ water mL = mg/mL). The calculator above does this automatically.
For Melanotan-2 specifically, 10 mg vials are common. A typical reconstitution adds 2 mL of bacteriostatic water, producing a concentration of 5 mg/mL for the 10 mg vial size.
Melanotan-2 half-life and storage
Published pharmacokinetic data reports a plasma half-life on the order of hours for Melanotan-2.
Lyophilized Melanotan-2 is typically stored refrigerated or frozen. Reconstituted solutions are commonly refrigerated and protected from light.
Common Melanotan-2 dosing mistakes
- Confusing mg and mcg. 1 mg = 1,000 mcg. Always convert to the same unit before computing the draw.
- Using a U-40 syringe with U-100 math. Same printed mark, 2.5× the physical volume. Always check the syringe label.
- Not labeling the vial. Write the reconstitution date and concentration on the vial the moment you mix it.
- Under-diluting. If your draw is less than about 1 unit, the volume is too small to read accurately — add more bacteriostatic water next time.