5-Amino-1MQ Calculator
Dosage and reconstitution math for 5-Amino-1MQ. A small-molecule inhibitor of nicotinamide N-methyltransferase studied for its effect on intracellular NAD+ availability.
Reconstitution calculator
Pre-filled with common defaults for 5-Amino-1MQ. Adjust any field to match your own vial.
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Enter values above to see the step-by-step math.
Free Illustrated Reconstitution Guide (PDF)
8-step visual walkthrough with photos and tips — from gathering supplies to drawing your dose. Educational only — not medical advice.
5-Amino-1MQ dosage calculator
The 5-Amino-1MQ dosage calculator above converts a target dose into exact syringe units based on your vial size and how much bacteriostatic water you used to reconstitute it. 5-Amino-1MQ is commonly sold in 50 mg, 100 mg vials. The calculator supports both U-100 and U-40 insulin syringes and flags draws that are too large for the syringe barrel or too small to measure accurately. A small-molecule inhibitor of nicotinamide N-methyltransferase studied for its effect on intracellular NAD+ availability. Enter your target dose in the calculator above to see the exact number of units to draw.
5-Amino-1MQ dosage chart
| Sample dose | Concentration | Volume to draw | Units on U-100 |
|---|---|---|---|
| 1.9 mg | 16.66667 mg/mL | 0.114 mL | 11.4 |
| 3.8 mg | 16.66667 mg/mL | 0.228 mL | 22.8 |
| 7.5 mg | 16.66667 mg/mL | 0.45 mL | 45 |
| 15 mg | 16.66667 mg/mL | 0.9 mL | 90 |
| 30 mg | 16.66667 mg/mL | 1.8 mL | 180 |
5-Amino-1MQ and NNMT inhibitor peptides
5-Amino-1MQ is a Small-molecule NNMT inhibitor (not a peptide). A small-molecule inhibitor of nicotinamide N-methyltransferase studied for its effect on intracellular NAD+ availability.
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). It is not a peptide but is commonly sold alongside peptide products. Published research has studied 5-amino-1MQ in cell and animal models of adipocyte metabolism, NAD+ homeostasis, and white adipose tissue biology, based on the premise that NNMT inhibition can increase intracellular NAD+ availability. 5-Amino-1MQ is not approved by the FDA for human use. Research-grade material is sold only as a laboratory reagent.
See all NNMT inhibitor peptides →
How to reconstitute 5-Amino-1MQ
Research vendors typically offer 5-amino-1MQ in 50 mg or 100 mg lyophilized vials. Reconstitution with 2–5 mL of bacteriostatic water is commonly reported for injectable research preparations.
Reconstituting 5-Amino-1MQ is the same unit-conversion process used for any lyophilized peptide:
- Draw your chosen volume of bacteriostatic water into a syringe.
- Inject the bacteriostatic water slowly down the side of the 5-Amino-1MQ vial — do not shoot it directly onto the powder.
- Swirl gently until the powder fully dissolves. Do not shake.
- Store the reconstituted vial refrigerated.
- To dose, calculate your draw volume: divide your target dose by the concentration (vial mg ÷ water mL = mg/mL). The calculator above does this automatically.
For 5-Amino-1MQ specifically, 50 mg, 100 mg vials are common. A typical reconstitution adds 2 mL of bacteriostatic water, producing a concentration of 50 mg/mL for the 100 mg vial size.
5-Amino-1MQ half-life and storage
Published pharmacokinetic data on 5-amino-1MQ in humans is limited. As a small molecule, it is generally reported to have a plasma half-life on the order of hours in preclinical models.
Lyophilized 5-amino-1MQ is typically stored refrigerated or frozen. Reconstituted solutions are commonly refrigerated and protected from light.
Common 5-Amino-1MQ dosing mistakes
Most 5-Amino-1MQ draw errors are unit errors, not arithmetic errors: confusing mg with mcg (1 mg = 1,000 mcg), or reading a U-40 syringe with U-100 math — the same printed mark holds 2.5× the volume. Two more worth avoiding: leaving the vial unlabeled, so the concentration and reconstitution date are lost, and under-diluting to the point where the draw is under about one unit and can no longer be read accurately.
Each of these is covered in full in the guides: reconstitution math from first principles, U-100 vs U-40 syringes, storage and shelf life, and how to reconstitute peptides.
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Related peptides
Published research on 5-Amino-1MQ
Indexed in PubMed. Listed for reference only — none of this is dosing guidance, and their presence here is not an endorsement of use.
- Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle Biochem Pharmacol, 2019 · PMID 30753815
- Nicotinamide n-methyltransferase inhibitor synergizes with sodium-glucose cotransporter 2 inhibitor to protect renal tubular epithelium in experimental models of type 2 diabetes mellitus J Diabetes Complications, 2025 · PMID 39848127
- Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice Sci Rep, 2021 · PMID 33707534
- Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice Sci Rep, 2022 · PMID 35013352
General resources: PubMed, DailyMed, ClinicalTrials.gov.