Epithalon Calculator

Epithalon dosage calculator

The Epithalon dosage calculator above converts a target dose into exact syringe units based on your vial size and how much bacteriostatic water you used to reconstitute it. Epithalon is commonly sold in 10 mg, 20 mg, 50 mg, 100 mg vials. The calculator supports both U-100 and U-40 insulin syringes and flags draws that are too large for the syringe barrel or too small to measure accurately. A synthetic tetrapeptide analog of the larger polypeptide epithalamin, studied for telomerase-related and circadian signaling mechanisms. Enter your target dose in the calculator above to see the exact number of units to draw.

Epithalon dosage chart

Epithalon and Tetrapeptide peptides

Epithalon is a Synthetic tetrapeptide (Ala-Glu-Asp-Gly). A synthetic tetrapeptide analog of the larger polypeptide epithalamin, studied for telomerase-related and circadian signaling mechanisms.

Epithalon, also spelled epitalon, is a synthetic four-amino-acid peptide (alanine-glutamic acid-aspartic acid-glycine) originally described by Russian researchers led by Vladimir Khavinson. It was designed as a short synthetic analog of the larger polypeptide epithalamin isolated from pineal gland tissue. Published research — much of it from Russian laboratories — has studied epithalon in cell and animal models in the contexts of telomerase activity, circadian regulation, and aging-related outcomes. Western peer-reviewed replication is more limited. Epithalon is not approved by the FDA for human use. Research-grade epithalon is labeled for laboratory research only.

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How to reconstitute Epithalon

Research vendors typically offer epithalon in 10 mg, 20 mg, 50 mg, or 100 mg lyophilized vials. Reconstitution with 2–5 mL of bacteriostatic water is commonly reported.

Reconstituting Epithalon is the same unit-conversion process used for any lyophilized peptide:

1. Draw your chosen volume of bacteriostatic water into a syringe.
2. Inject the bacteriostatic water slowly down the side of the Epithalon vial — do not shoot it directly onto the powder.
3. Swirl gently until the powder fully dissolves. Do not shake.
4. Store the reconstituted vial refrigerated.
5. To dose, calculate your draw volume: divide your target dose by the concentration (vial mg ÷ water mL = mg/mL). The calculator above does this automatically.

For Epithalon specifically, 10 mg, 20 mg, 50 mg, 100 mg vials are common. A typical reconstitution adds 2 mL of bacteriostatic water, producing a concentration of 25 mg/mL for the 50 mg vial size.

Epithalon half-life and storage

As a very short unmodified tetrapeptide, epithalon is expected to have a short plasma half-life on the order of minutes, though downstream effects measured in research models may persist longer.

Lyophilized epithalon is typically stored refrigerated or frozen. Reconstituted solutions are commonly refrigerated and protected from light.

Common Epithalon dosing mistakes

Most Epithalon draw errors are unit errors, not arithmetic errors: confusing mg with mcg (1 mg = 1,000 mcg), or reading a U-40 syringe with U-100 math — the same printed mark holds 2.5× the volume. Two more worth avoiding: leaving the vial unlabeled, so the concentration and reconstitution date are lost, and under-diluting to the point where the draw is under about one unit and can no longer be read accurately.

Each of these is covered in full in the guides: reconstitution math from first principles, U-100 vs U-40 syringes, storage and shelf life, and how to reconstitute peptides.

Epithalon stacks

Epithalon is one of the ingredients in what is commonly referred to as the Longevity stack . These are terms used in online peptide communities to describe specific combinations. See the stack pages for the full composition and calculator links.