Thymosin Alpha-1 Calculator

Thymosin Alpha-1 dosage calculator

The Thymosin Alpha-1 dosage calculator above converts a target dose into exact syringe units based on your vial size and how much bacteriostatic water you used to reconstitute it. Thymosin Alpha-1 is commonly sold in 5 mg, 10 mg vials. The calculator supports both U-100 and U-40 insulin syringes and flags draws that are too large for the syringe barrel or too small to measure accurately. A 28-amino-acid peptide originally isolated from thymic tissue, studied for its effects on T-cell maturation and cytokine signaling. Enter your target dose in the calculator above to see the exact number of units to draw.

Thymosin Alpha-1 dosage chart

Thymosin Alpha-1 and Thymic peptides

Thymosin Alpha-1 is a Synthetic 28-amino-acid thymic peptide. A 28-amino-acid peptide originally isolated from thymic tissue, studied for its effects on T-cell maturation and cytokine signaling.

Thymosin alpha-1 is a 28-amino-acid peptide originally isolated from thymic tissue. Published research has studied its effects on immune-cell signaling, particularly T-cell maturation and cytokine modulation. Synthetic thymosin alpha-1 has been approved for clinical use in a number of countries outside the United States under the brand name Zadaxin for specific infectious and oncological indications, and has been the subject of clinical trials in viral hepatitis and immune dysfunction. It is not approved by the FDA for human use in the United States. Research-grade thymosin alpha-1 from chemical supply companies is labeled for laboratory research only.

See all Thymic peptides →

How to reconstitute Thymosin Alpha-1

Research vendors typically offer thymosin alpha-1 in 5 mg or 10 mg lyophilized vials. Reconstitution with 2–3 mL of bacteriostatic water is common.

Reconstituting Thymosin Alpha-1 is the same unit-conversion process used for any lyophilized peptide:

1. Draw your chosen volume of bacteriostatic water into a syringe.
2. Inject the bacteriostatic water slowly down the side of the Thymosin Alpha-1 vial — do not shoot it directly onto the powder.
3. Swirl gently until the powder fully dissolves. Do not shake.
4. Store the reconstituted vial refrigerated.
5. To dose, calculate your draw volume: divide your target dose by the concentration (vial mg ÷ water mL = mg/mL). The calculator above does this automatically.

For Thymosin Alpha-1 specifically, 5 mg, 10 mg vials are common. A typical reconstitution adds 2 mL of bacteriostatic water, producing a concentration of 5 mg/mL for the 10 mg vial size.

Thymosin Alpha-1 half-life and storage

Published pharmacokinetic studies on synthetic thymosin alpha-1 report a plasma half-life of approximately 2 hours.

Lyophilized thymosin alpha-1 is typically stored refrigerated at 2–8 °C. Reconstituted solutions are generally reported to be kept refrigerated with light protection; stability is commonly reported in literature and manufacturer inserts.

Common Thymosin Alpha-1 dosing mistakes

Most Thymosin Alpha-1 draw errors are unit errors, not arithmetic errors: confusing mg with mcg (1 mg = 1,000 mcg), or reading a U-40 syringe with U-100 math — the same printed mark holds 2.5× the volume. Two more worth avoiding: leaving the vial unlabeled, so the concentration and reconstitution date are lost, and under-diluting to the point where the draw is under about one unit and can no longer be read accurately.

Each of these is covered in full in the guides: reconstitution math from first principles, U-100 vs U-40 syringes, storage and shelf life, and how to reconstitute peptides.