Ipamorelin Reconstitution Calculator

What is Ipamorelin?

Ipamorelin is a synthetic pentapeptide belonging to the growth hormone releasing peptide (GHRP) class. Published research has studied its agonism at the ghrelin / growth hormone secretagogue receptor (GHSR) and its effect on pulsatile growth hormone release. It has been characterized in the literature as more selective than earlier GHRPs such as GHRP-6 and GHRP-2 because it has shown minimal effect on cortisol and prolactin in reported studies. Ipamorelin is not approved by the FDA for human use. Research-grade ipamorelin sold by chemical supply companies is labeled for laboratory research purposes only.

Common vial sizes

Research vendors typically offer ipamorelin in 2 mg, 5 mg, or 10 mg lyophilized vials. Reconstitution with 2–3 mL of bacteriostatic water is commonly reported.

• 2 mg vial
• 5 mg vial
• 10 mg vial

Reconstitution examples

Worked examples showing exactly what a given vial, bacteriostatic water volume, and target dose produce in syringe units. All math is from the same calculator above.

• 5 mg vial + 2 mL bacteriostatic water → 2500 mcg/mL concentration.
  A 200 mcg dose = 8 units on a u-100 insulin, 1 ml (100 units) (0.08 mL).
• 5 mg vial + 2 mL bacteriostatic water → 2500 mcg/mL concentration.
  A 300 mcg dose = 12 units on a u-100 insulin, 1 ml (100 units) (0.12 mL).
• 10 mg vial + 3 mL bacteriostatic water → 3333.33 mcg/mL concentration.
  A 300 mcg dose = 9 units on a u-100 insulin, 1 ml (100 units) (0.09 mL).
• 2 mg vial + 2 mL bacteriostatic water → 1000 mcg/mL concentration.
  A 100 mcg dose = 10 units on a u-100 insulin, 1 ml (100 units) (0.1 mL).

Storage & shelf life

Lyophilized ipamorelin is typically stored refrigerated at 2–8 °C. Reconstituted solutions are generally kept refrigerated and protected from light.

Reported half-life

Published pharmacokinetic studies report a plasma half-life of approximately 2 hours for ipamorelin.