AOD-9604 Reconstitution Calculator

What is AOD-9604?

AOD-9604 is a synthetic peptide corresponding to the C-terminal fragment (amino acids 176–191) of human growth hormone, with an additional N-terminal tyrosine residue. Published research has studied AOD-9604 in animal and cell models of lipolysis and fat metabolism. The literature characterizes it as having been investigated for lipolytic activity without the classical growth-promoting or insulin-antagonistic effects of full-length growth hormone. AOD-9604 is not approved by the FDA for human use; it has been notified as a GRAS ingredient in certain food contexts in some jurisdictions, which is a separate regulatory category from injection. Research-grade AOD-9604 is labeled for laboratory research only.

Common vial sizes

Research vendors typically offer AOD-9604 in 2 mg or 5 mg lyophilized vials. Reconstitution with 2–3 mL of bacteriostatic water is commonly reported.

• 2 mg vial
• 5 mg vial

Reconstitution examples

Worked examples showing exactly what a given vial, bacteriostatic water volume, and target dose produce in syringe units. All math is from the same calculator above.

• 5 mg vial + 2 mL bacteriostatic water → 2500 mcg/mL concentration.
  A 300 mcg dose = 12 units on a u-100 insulin, 1 ml (100 units) (0.12 mL).
• 5 mg vial + 2 mL bacteriostatic water → 2500 mcg/mL concentration.
  A 500 mcg dose = 20 units on a u-100 insulin, 1 ml (100 units) (0.2 mL).
• 2 mg vial + 2 mL bacteriostatic water → 1000 mcg/mL concentration.
  A 300 mcg dose = 30 units on a u-100 insulin, 1 ml (100 units) (0.3 mL).
• 5 mg vial + 3 mL bacteriostatic water → 1666.67 mcg/mL concentration.
  A 500 mcg dose = 30 units on a u-100 insulin, 1 ml (100 units) (0.3 mL).

Storage & shelf life

Lyophilized AOD-9604 is typically stored refrigerated. Reconstituted solutions are commonly refrigerated and protected from light.

Reported half-life

Published pharmacokinetic data on AOD-9604 is limited. As a small peptide fragment, the parent compound is expected to have a short plasma half-life on the order of minutes, though downstream effects may persist longer.