PT-141 (Bremelanotide) Calculator
Dosage and reconstitution math for PT-141 (Bremelanotide). A melanocortin receptor agonist metabolite of Melanotan-2 with activity directed at the MC4R receptor subtype.
Reconstitution calculator
Pre-filled with common defaults for PT-141 (Bremelanotide). Adjust any field to match your own vial.
Show the math
Enter values above to see the step-by-step math.
Free Illustrated Reconstitution Guide (PDF)
8-step visual walkthrough with photos and tips — from gathering supplies to drawing your dose. Educational only — not medical advice.
PT-141 (Bremelanotide) dosage calculator
The PT-141 (Bremelanotide) dosage calculator above converts a target dose into exact syringe units based on your vial size and how much bacteriostatic water you used to reconstitute it. PT-141 (Bremelanotide) is commonly sold in 10 mg vials. The calculator supports both U-100 and U-40 insulin syringes and flags draws that are too large for the syringe barrel or too small to measure accurately. A melanocortin receptor agonist metabolite of Melanotan-2 with activity directed at the MC4R receptor subtype. Enter your target dose in the calculator above to see the exact number of units to draw.
PT-141 (Bremelanotide) dosage chart
| Sample dose | Concentration | Volume to draw | Units on U-100 |
|---|---|---|---|
| 0.25 mg | 3.33333 mg/mL | 0.075 mL | 7.5 |
| 0.5 mg | 3.33333 mg/mL | 0.15 mL | 15 |
| 1 mg | 3.33333 mg/mL | 0.3 mL | 30 |
| 2 mg | 3.33333 mg/mL | 0.6 mL | 60 |
| 4 mg | 3.33333 mg/mL | 1.2 mL | 120 |
PT-141 (Bremelanotide) and Melanocortin peptides
PT-141 (Bremelanotide) is a Melanocortin-4 receptor agonist. A melanocortin receptor agonist metabolite of Melanotan-2 with activity directed at the MC4R receptor subtype. Other peptides in the Melanocortin class include Melanotan-2 .
See all Melanocortin peptides →
How to reconstitute PT-141 (Bremelanotide)
Reconstituting PT-141 (Bremelanotide) is the same unit-conversion process used for any lyophilized peptide:
- Draw your chosen volume of bacteriostatic water into a syringe.
- Inject the bacteriostatic water slowly down the side of the PT-141 (Bremelanotide) vial — do not shoot it directly onto the powder.
- Swirl gently until the powder fully dissolves. Do not shake.
- Store the reconstituted vial refrigerated.
- To dose, calculate your draw volume: divide your target dose by the concentration (vial mg ÷ water mL = mg/mL). The calculator above does this automatically.
For PT-141 (Bremelanotide) specifically, 10 mg vials are common. A typical reconstitution adds 2 mL of bacteriostatic water, producing a concentration of 5 mg/mL for the 10 mg vial size.
PT-141 (Bremelanotide) half-life and storage
Published pharmacokinetic studies report a plasma half-life of approximately 2 hours for PT-141 / bremelanotide.
Lyophilized PT-141 is typically stored refrigerated. Reconstituted solutions are commonly refrigerated and protected from light.
Common PT-141 (Bremelanotide) dosing mistakes
- Confusing mg and mcg. 1 mg = 1,000 mcg. Always convert to the same unit before computing the draw.
- Using a U-40 syringe with U-100 math. Same printed mark, 2.5× the physical volume. Always check the syringe label.
- Not labeling the vial. Write the reconstitution date and concentration on the vial the moment you mix it.
- Under-diluting. If your draw is less than about 1 unit, the volume is too small to read accurately — add more bacteriostatic water next time.