SS-31 (Elamipretide) Calculator
Dosage and reconstitution math for SS-31 (Elamipretide). A mitochondrial-targeted tetrapeptide that binds cardiolipin on the inner mitochondrial membrane to modulate electron transport chain function.
Reconstitution calculator
Pre-filled with common defaults for SS-31 (Elamipretide). Adjust any field to match your own vial.
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Enter values above to see the step-by-step math.
Free Illustrated Reconstitution Guide (PDF)
8-step visual walkthrough with photos and tips — from gathering supplies to drawing your dose. Educational only — not medical advice.
SS-31 (Elamipretide) dosage calculator
The SS-31 (Elamipretide) dosage calculator above converts a target dose into exact syringe units based on your vial size and how much bacteriostatic water you used to reconstitute it. SS-31 (Elamipretide) is commonly sold in 5 mg, 10 mg, 50 mg vials. The calculator supports both U-100 and U-40 insulin syringes and flags draws that are too large for the syringe barrel or too small to measure accurately. A mitochondrial-targeted tetrapeptide that binds cardiolipin on the inner mitochondrial membrane to modulate electron transport chain function. Enter your target dose in the calculator above to see the exact number of units to draw.
SS-31 (Elamipretide) dosage chart
| Sample dose | Concentration | Volume to draw | Units on U-100 |
|---|---|---|---|
| 0.25 mg | 3.33333 mg/mL | 0.075 mL | 7.5 |
| 0.5 mg | 3.33333 mg/mL | 0.15 mL | 15 |
| 1 mg | 3.33333 mg/mL | 0.3 mL | 30 |
| 2 mg | 3.33333 mg/mL | 0.6 mL | 60 |
| 4 mg | 3.33333 mg/mL | 1.2 mL | 120 |
SS-31 (Elamipretide) and Mitochondrial peptides
SS-31 (Elamipretide) is a Mitochondrial-targeted tetrapeptide. A mitochondrial-targeted tetrapeptide that binds cardiolipin on the inner mitochondrial membrane to modulate electron transport chain function. Other peptides in the Mitochondrial class include MOTS-c .
See all Mitochondrial peptides →
How to reconstitute SS-31 (Elamipretide)
Reconstituting SS-31 (Elamipretide) is the same unit-conversion process used for any lyophilized peptide:
- Draw your chosen volume of bacteriostatic water into a syringe.
- Inject the bacteriostatic water slowly down the side of the SS-31 (Elamipretide) vial — do not shoot it directly onto the powder.
- Swirl gently until the powder fully dissolves. Do not shake.
- Store the reconstituted vial refrigerated.
- To dose, calculate your draw volume: divide your target dose by the concentration (vial mg ÷ water mL = mg/mL). The calculator above does this automatically.
For SS-31 (Elamipretide) specifically, 5 mg, 10 mg, 50 mg vials are common. A typical reconstitution adds 2 mL of bacteriostatic water, producing a concentration of 5 mg/mL for the 10 mg vial size.
SS-31 (Elamipretide) half-life and storage
Published pharmacokinetic studies report a plasma half-life of approximately 3–4 hours for SS-31 / elamipretide.
Lyophilized SS-31 is typically stored refrigerated. Reconstituted solutions are commonly refrigerated and protected from light.
Common SS-31 (Elamipretide) dosing mistakes
- Confusing mg and mcg. 1 mg = 1,000 mcg. Always convert to the same unit before computing the draw.
- Using a U-40 syringe with U-100 math. Same printed mark, 2.5× the physical volume. Always check the syringe label.
- Not labeling the vial. Write the reconstitution date and concentration on the vial the moment you mix it.
- Under-diluting. If your draw is less than about 1 unit, the volume is too small to read accurately — add more bacteriostatic water next time.