LL-37 Calculator
Dosage and reconstitution math for LL-37. A human cathelicidin antimicrobial peptide derived from hCAP-18, studied for innate immune and antimicrobial mechanisms.
Reconstitution calculator
Pre-filled with common defaults for LL-37. Adjust any field to match your own vial.
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Enter values above to see the step-by-step math.
Free Illustrated Reconstitution Guide (PDF)
8-step visual walkthrough with photos and tips — from gathering supplies to drawing your dose. Educational only — not medical advice.
LL-37 dosage calculator
The LL-37 dosage calculator above converts a target dose into exact syringe units based on your vial size and how much bacteriostatic water you used to reconstitute it. LL-37 is commonly sold in 5 mg, 10 mg vials. The calculator supports both U-100 and U-40 insulin syringes and flags draws that are too large for the syringe barrel or too small to measure accurately. A human cathelicidin antimicrobial peptide derived from hCAP-18, studied for innate immune and antimicrobial mechanisms. Enter your target dose in the calculator above to see the exact number of units to draw.
LL-37 dosage chart
| Sample dose | Concentration | Volume to draw | Units on U-100 |
|---|---|---|---|
| 190 mcg | 2.5 mg/mL | 0.076 mL | 7.6 |
| 380 mcg | 2.5 mg/mL | 0.152 mL | 15.2 |
| 750 mcg | 2.5 mg/mL | 0.3 mL | 30 |
| 1500 mcg | 2.5 mg/mL | 0.6 mL | 60 |
| 3000 mcg | 2.5 mg/mL | 1.2 mL | 120 |
LL-37 and Antimicrobial peptides
LL-37 is a Human cathelicidin antimicrobial peptide. A human cathelicidin antimicrobial peptide derived from hCAP-18, studied for innate immune and antimicrobial mechanisms.
See all Antimicrobial peptides →
How to reconstitute LL-37
Reconstituting LL-37 is the same unit-conversion process used for any lyophilized peptide:
- Draw your chosen volume of bacteriostatic water into a syringe.
- Inject the bacteriostatic water slowly down the side of the LL-37 vial — do not shoot it directly onto the powder.
- Swirl gently until the powder fully dissolves. Do not shake.
- Store the reconstituted vial refrigerated.
- To dose, calculate your draw volume: divide your target dose by the concentration (vial mg ÷ water mL = mg/mL). The calculator above does this automatically.
For LL-37 specifically, 5 mg, 10 mg vials are common. A typical reconstitution adds 2 mL of bacteriostatic water, producing a concentration of 5 mg/mL for the 10 mg vial size.
LL-37 half-life and storage
Published pharmacokinetic data on systemic LL-37 is limited. Available research suggests a plasma half-life on the order of hours.
Lyophilized LL-37 is typically stored frozen for long-term storage or refrigerated for short-term use. Reconstituted solutions are commonly kept refrigerated and protected from light.
Common LL-37 dosing mistakes
- Confusing mg and mcg. 1 mg = 1,000 mcg. Always convert to the same unit before computing the draw.
- Using a U-40 syringe with U-100 math. Same printed mark, 2.5× the physical volume. Always check the syringe label.
- Not labeling the vial. Write the reconstitution date and concentration on the vial the moment you mix it.
- Under-diluting. If your draw is less than about 1 unit, the volume is too small to read accurately — add more bacteriostatic water next time.