Tesamorelin Calculator

Tesamorelin dosage calculator

The Tesamorelin dosage calculator above converts a target dose into exact syringe units based on your vial size and how much bacteriostatic water you used to reconstitute it. Tesamorelin is commonly sold in 2 mg, 5 mg, 10 mg vials. The calculator supports both U-100 and U-40 insulin syringes and flags draws that are too large for the syringe barrel or too small to measure accurately. A stabilized GHRH analog with an N-terminal modification that increases metabolic stability relative to native GHRH. Enter your target dose in the calculator above to see the exact number of units to draw.

Tesamorelin dosage chart

Tesamorelin and GHRH peptides

Tesamorelin is a Stabilized GHRH analog. A stabilized GHRH analog with an N-terminal modification that increases metabolic stability relative to native GHRH. The same molecule is the active ingredient in Egrifta, which are FDA-approved prescription medications manufactured by their respective companies. Research-use Tesamorelin is regulated differently and is not approved for human consumption. Other peptides in the GHRH class include CJC-1295 (no DAC) , CJC-1295 with DAC , and Sermorelin .

Tesamorelin is a synthetic analog of growth hormone releasing hormone (GHRH) with an N-terminal modification (a trans-3-hexenoic acid group) that increases its stability relative to native GHRH and sermorelin. Published clinical research has studied tesamorelin for its effects on visceral adipose tissue and has been the subject of trials in HIV-associated lipodystrophy. Tesamorelin has been approved by the FDA under the brand name Egrifta for reduction of excess abdominal fat in HIV patients with lipodystrophy. Research-grade tesamorelin from chemical supply companies is labeled for laboratory use only and is distinct from the approved pharmaceutical product.

See all GHRH peptides →

How to reconstitute Tesamorelin

Research vendors typically offer tesamorelin in 2 mg, 5 mg, or 10 mg lyophilized vials. Reconstitution with 2–3 mL of bacteriostatic water is commonly reported.

Reconstituting Tesamorelin is the same unit-conversion process used for any lyophilized peptide:

1. Draw your chosen volume of bacteriostatic water into a syringe.
2. Inject the bacteriostatic water slowly down the side of the Tesamorelin vial — do not shoot it directly onto the powder.
3. Swirl gently until the powder fully dissolves. Do not shake.
4. Store the reconstituted vial refrigerated.
5. To dose, calculate your draw volume: divide your target dose by the concentration (vial mg ÷ water mL = mg/mL). The calculator above does this automatically.

For Tesamorelin specifically, 2 mg, 5 mg, 10 mg vials are common. A typical reconstitution adds 2 mL of bacteriostatic water, producing a concentration of 2.5 mg/mL for the 5 mg vial size.

Tesamorelin half-life and storage

Published pharmacokinetic studies report a plasma half-life of approximately 26 minutes for tesamorelin.

Lyophilized tesamorelin is typically stored refrigerated. The approved branded product Egrifta has published stability data for the reconstituted solution, typically in the range of several hours at room temperature or longer under refrigeration.

Common Tesamorelin dosing mistakes

Most Tesamorelin draw errors are unit errors, not arithmetic errors: confusing mg with mcg (1 mg = 1,000 mcg), or reading a U-40 syringe with U-100 math — the same printed mark holds 2.5× the volume. Two more worth avoiding: leaving the vial unlabeled, so the concentration and reconstitution date are lost, and under-diluting to the point where the draw is under about one unit and can no longer be read accurately.

Each of these is covered in full in the guides: reconstitution math from first principles, U-100 vs U-40 syringes, storage and shelf life, and how to reconstitute peptides.